Supply Lemon extract DIOSMETIN 98% CAS NO.520-34-3

Commercial Diosmin is obtained by chemical synthesis from hesperidin (extracted from immature citrus fruit).Diosmin is greyish-yellow or light yellow hygroscopic powder,practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides. Melting point is 275-277 °C when purity is 95% tested by HPLC.

Scientific support

Diosmin was first isolated in 1925 from Scrophularia nodosa, and first introduced as a therapeutic agent in 1969. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.

Diosmin differs molecularly from hesperidin by the presence of a double bond between two carbon atoms in diosmin’s central carbon ring. Diosmin can be manufactured by extracting hesperidin from citrus rinds, followed by conversion of hesperidin to diosmin. Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.

Chemical Name: DIOSMETIN
CAS No.: 520-34-3

Chemical Structure: C16H12O6

Molecular weight: 300.26

Appearance: Yellow powder

Assay: 98%min

 1.Diosmetin has the function antioxidant, anti-infection, shock, etc

2.Diosmetin can be used as food, cosmetics and future drug.

3.Diosmetin has the anti-mutagenesis and the anti-allergy characteristic.

4.Pelargonium wood known antioxidant, anti-infective, anti-shock efficacy of functional food, cosmetic and future drugs. Inhibition of CYP1A enzyme activity of a natural flavonoids. Pelargonium lignin also has anti-mutagenic and anti-allergic properties.

1. As food additive, diosmetin powder is widely used in the field of food and health products;

2. As the acid to speed up the horny update, diosmetin powder is widely used in the field of cosmetic;

3. As dietary supplements increased therapeutic function,diosmetin powder is widely used in fields ofdietary supplement products;