Supply Sophora japonica extract Genistein 98% 446-72-0 CAS NO.446-72-0

Genistein is a major active factor in soy isoflavones and is the most effective functional ingredient in soy isoflavones with a variety of physiological functions. Genistein is structurally similar to mammalian estrogen-estradiol and has an active group of estrogen-diphenolic hydroxyl group, so genistein has various physiological activities such as estrogenic activity.

Genistein, which is present in Sophora japonica, is soluble in DMSO and ethanol and is almost insoluble in water. With estrogen and anti-estrogen properties; It has anti-oxidant effect; it can inhibit the activity of tyrosine protein kinase (PTK); it can inhibit the activity of topoisomeric enzyme II; it can induce programmed cell death, improve the anti-cancer drug effect, and inhibit angiogenesis.

Genistein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, and other legumes. The estimated human normal dietary intake of genistein, primarily as glycosides, is 0 to 0.5 mg/kg. Genistein is present in much greater amounts in nutritional supplements. Genistein is carcinogenic in female neonatal mice, inducing endocrine-dependent uterine tumors in a fashion similar to diethylstilbestrol (DES). 

Chemical Name: Genistein
CAS No.: 446-72-0

Chemical Structure: C15H10O5

Molecular weight: 270.24

Appearance: Light yellow powder

Assay: 98%min

<sub>1. Genistein Powder has the function of anti-oxidation;
2. Genistein powder has the properties of estrogen and anti-estrogen;
3.GenisteinPowdercan suppress the activation of topoisomerase II, and suppress the activation of protein</sub> 

<sub>tyrosine kinase;
4. Genistein Powder brings out cell's procedure death, improves the anticancer drug's effect and suppresses the</sub> 

_{blood vessel to be produced etc.}

_{1. Applied in the field of pharmaceutical,genistin can be made into suppositories, lotions, injection, tablets,}

_{capsules and so on;
2. Applied in the field of health care products,genistein can be used as beauty care products for women and also it can prevent blood diseases and cancer.}