Supply Rhubarb extract Chrysophanic acid 98% 481-74-3 CAS NO.481-74-3

Chrysophanol (CHR) is one of traditional Chinese medicine which was reported to show protective effects in cognition dysfunction and inflammatory in previously studies. In this current study, whether CHR protects learning and memory dysfunctions induced by diabetes disease or not and underlying mechanisms were studied.

Chrysophanic has the unique curative effect of improving glucose metabolism abnormality, reversing insulin resistance, effectively preventing diabetic nephropathy, and new pharmacodynamic characteristics. It is known to be useful for treating diabetic
nephropathy, and has good safety. The researchers conducted systematic in vitro and in vivo studies on rhein. It was found that rhein inhibits the activity of glucosamine pathway in cell sugar metabolism by inhibiting the function of glucose transporter 1 and inhibits the expression of PAI-1 in endothelial cells.
The function of endothelial cells and the mechanism of reversing insulin resistance play a role in the treatment of diabetic nephropathy, which are new mechanisms of action in the treatment of diabetic nephropathy. Its efficacy has been given in a series of animal models, such as type 1 diabetic nephropathy (STZ rat model, NOD mouse model) and type 2 diabetic nephropathy (high glucose and high fat diet model, db/db mouse model) model. verification. There is no similar international treatment for this new material for the treatment of diabetic nephropathy.

Chemical Name: Chrysophanic acid
CAS No.: 481-74-3

Chemical Structure: C15H10O4

Molecular weight: 254.24

Appearance: Yellow powder

Assay: 98%min

1.Chrysophanol is used for anti-aging, regulating the activity of central nervous system, thus to delay the aging of brain;

2. Chrysophanol can delay thymus degradation which caused by aging , improve immunity of body;

3. Chrysophanol has the function of protecting liver.

4. Chrysophanol can improve the ability of reducing the cholesterol, lowering blood fat and inhibit the development of atherosclerotic;

5. Chrysophanol is good for liver which can increase the function of hepatic glycogen.

6. It has obvious antitussive effect.

7. It can inhibit the streptococcus A, pneumococcus, influenza bacillus and catarrhal bacteria to different degrees.

8. It can promote the movement of the intestinal tract. Rat experiments have shown that this product has a diuretic effect.

9. It can be used for anti-aging.

1. Applied in comestics, rhubarb extract can delay aging and prevent UV radiation.

2. Applied in food field, rhubarb extract is used as food additive with the function of lengthening life.

3. Applied in pharmaceutical field, rhubarb extract is frequently used as medicine supplement or OTCS Ingredients and owns good efficacy for treatment of cancer and cardio-cerebrovascular disease.